Application of 1194-22-5. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 6-Hydroxy-2-methylpyrimidin-4(3H)-one, is researched, Molecular C5H6N2O2, CAS is 1194-22-5, about Influence of some derivatives and isomers of uracil, cytosine, and isocytosine on the growth of transplantable tumors. Author is Aksamitnaya, I. A..
5-Hydroxy-4-methyluracil, 4,5-dihydrouracil, 6-thiouracil, 6-thio-4-methyluracil, 2-methyl-4,6-dihydroxypyrimidine, or 4-amino-6-hydroxypyrimidine at 100-200 mg./ml. suppressed tumor growth by 9-32%, while 6-thiothymine and Na 4-methyl-5-sulfoisocytosine stimulated tumor growth by 33 and 41%, resp., in mice implanted with sarcoma 180 cells. 4-Amino-6-hydroxypyrimidine inhibited and Na 4-methyl-5-sulfoisocytosine stimulated growth of Ehrlich ascites tumors in mice. Thymine, 4-methyluracil, 4-methyl-4,5-dihydrouracil, 4-methylisocytosine, and 4-methyl-5-aminoisocytosine did not affect tumor growth in mice.
There is still a lot of research devoted to this compound(SMILES:CC1=NC(=CC(N1)=O)O)Application of 1194-22-5, and with the development of science, more effects of this compound(1194-22-5) can be discovered.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem