(η3-Allyl)palladium complexes of chiral N,O-chelates: preparation, structures, and prospects for selective allylic functionalization was written by Yang, Hu; Khan, Masood A.; Nicholas, Kenneth M.. And the article was included in Organometallics on September 30,1993.Name: (R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol The following contents are mentioned in the article:
A series of (η3-allyl)Pd derivatives of chiral N,O-bidentate ligands have been prepared and characterized to assess their potential as model intermediates for regio- and stereocontrolled catalytic allylic oxidation and substitution reactions. [N-(α-methylbenzyl)salicylaldimine]-Pd(η3-cyclohexenyl) (I), which exists in solution as a 1:1 Pd-allyl rotameric (exo/endo) mixture, selectively crystallizes as a single isomer. The X-ray crystal structure of this isomer of I shows nearly sym. Pd-allyl bonding parameters and the N-α-Ph group endo to the flap of the cyclohexenyl ring. The new chiral 4-substituted salicyloxazoline ligands and the corresponding (salicyloxazoline)Pd(η3-cyclohexenyl) complexes (II, R = Ph, CMe3, etc.; R1 = H, NO2, OMe; R2 = H, NO2) have been prepared in good yields by treatment of {(η3-cyclohexenyl)PdCl}2 with the K derivatives of the ligands. Solution NMR studies of II indicate that the ratio of isomers is a function of the size of the α-N substituent, with single isomers being present for R = tert-Bu. X-ray anal. of II (R = CMe3, R1 = R2 = H) reveals that the tert-Bu group and the cyclohexenyl flap are in an exo relationship with little evidence for a differential ground-state trans influence derived from the unsym. chelate. The terminal allylic proton NMR resonances of II (R = CMe3) are separated by ca. 0.4-0.5 ppm, suggesting different electronic characters for the two allylic carbons. Reactivity studies show that the complexes II are relatively unreactive toward HOAc, giving varying amounts of allylic acetate, and toward the nucleophiles OAc- and CH(CO2CH3)2-. This study involved multiple reactions and reactants, such as (R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-10-8Name: (R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol).
(R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-10-8) belongs to oxazolidine derivatives. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.Name: (R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol
150699-10-8;(R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol;The future of 150699-10-8;New trend of C13H17NO2;function of 150699-10-8