In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthetic technology of 1-acetyl-4-(4-hydroxyphenyl)piperazine, published in 2005-06-20, which mentions a compound: 67914-60-7, mainly applied to acetyl hydroxyphenyl piperazine synthesis; ketoconazole intermediate hydroxyphenyl piperazinyl ethanone preparation, Reference of 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone.
An important intermediate of antifungal drug ketoconazole, 1-acetyl-4-(4-hydroxyphenyl)piperazine [i.e., 1-[4-(4-hydroxyphenyl)-1-piperazinyl]ethanone], was synthesized from piperazine-6H2O and p-chloronitrobenzene by substitution, N- acetylation with acetic anhydride, reduction with Ni/hydrazine, diazotization, and hydrolysis in the presence of Cu/Cu(NO3)2, and its possibility of com. use was studied. The compound was obtained with yield excelled present route. The route may be used in com. production (no data).
Here is a brief introduction to this compound(67914-60-7)Reference of 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone, if you want to know about other compounds related to this compound(67914-60-7), you can read my other articles.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem