In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called The effect of some derivatives of pyrimidine on metastasis of the transplantable rat sarcoma SSK, published in 1963, which mentions a compound: 1194-22-5, mainly applied to , Reference of 6-Hydroxy-2-methylpyrimidin-4(3H)-one.
Sarcoma SSK was transferred to normal rats by injection of a tumor cell suspension in physiol. saline containing penicillin into the middle third of the tail. Treatment by intraperitoneal injection of metacil (I), 2-methyl-4,6-dioxypyrimidine (II), thymine (III), dihydrothymine (IV), cytosine (V), isocytosine (VI), 4,6-dioxy-5-nitropyrimidine (VII), 2,6-mercapto-5-amino-4-methylpyrimidine (VIII), and pentoxyl (IX) in solution or suspension in physiol. saline in doses of 100 mg./kg./day was begun within 24 hrs., and continued for 19 days. Control animals received physiol. saline. In one group, the tails were amputated after 5 days; in the second, after 9 days. In the 1st group, animals which received VII all died in the postoperative period, while those which received I, II, V, VI, or IX developed fewer metastases than the controls. No such inhibitory effect of metastasis was observed in the 2nd group. In both groups, animals which received III, IV, or VIII developed more metastases than the controls.
In some applications, this compound(1194-22-5)Reference of 6-Hydroxy-2-methylpyrimidin-4(3H)-one is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem