Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2,6-Dichloropurine, is researched, Molecular C5H2Cl2N4, CAS is 5451-40-1, about Automated Nanomole-Scale Reaction Screening toward Benzoate Bioisosteres: A Photocatalyzed Approach to Highly Elaborated Bicyclo[1.1.1]Pentanes.Name: 2,6-Dichloropurine.
Through the application of high-throughput nanoscale optimization, a mild, photocatalyzed, Minisci-like protocol were developed to access highly functionalized 1,3-disubstituted bicyclopentanes. The benzoate-isosteric compounds were prepared using a readily available organic photocatalyst, mitigating the need for precious metals. The strategy described furnished products in synthetically useful yields and were demonstrated to be executable in parallel medicinal chem. format.
In addition to the literature in the link below, there is a lot of literature about this compound(2,6-Dichloropurine)Name: 2,6-Dichloropurine, illustrating the importance and wide applicability of this compound(5451-40-1).
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem