Diastereoselective synthesis of deprotectable isoxazolidines was written by Wang, Wentian;Rein, Kathleen S.. And the article was included in Tetrahedron Letters in 2013.COA of Formula: C6H7NO3 This article mentions the following:
Isoxazolidines are important synthetic targets due to their ability to act as nucleoside analogs. The 1,3-dipolar cycloaddition reaction of nitrones with alkenes is a powerful approach to the synthesis of isoxazolidines with the potential for control over absolute and relative stereoselectivity. However, removal of the most commonly used protecting groups without cleavage of the N-O bond is a significant challenge. The diastereoselective synthesis of benzhydryl protected isoxazolidines and the reductive cleavage of the benzhydryl protecting group with retention of the isoxazolidine ring are reported. In the experiment, the researchers used many compounds, for example, 3-Acryloyloxazolidin-2-one (cas: 2043-21-2COA of Formula: C6H7NO3).
3-Acryloyloxazolidin-2-one (cas: 2043-21-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.COA of Formula: C6H7NO3
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem