Iodine-catalyzed direct allylation of chiral oxazolidinones by the amide-aldehyde-alkene condensation was written by Wang, Tong-Lin;Qi, Hai-Tang;Wang, Xi-Cun;Quan, Zheng-Jun. And the article was included in Tetrahedron Letters in 2019.Formula: C9H9NO2 This article mentions the following:
An iodine-catalyzed direct allylation of chiral oxazolidinones with aldehydes and alkenes has been developed. The reaction, without use of any bases or metals, directly converted the 3-chiral oxazolidinones into N-allylated oxazolidinones. Addnl., the 3-chiral allylamine skeleton was constructed and the diastereomers were isolated by simple column chromatog. In the experiment, the researchers used many compounds, for example, (S)-4-Phenyloxazolidin-2-one (cas: 99395-88-7Formula: C9H9NO2).
(S)-4-Phenyloxazolidin-2-one (cas: 99395-88-7) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries.Formula: C9H9NO2
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem