Vinay Kumar, Koravangala S.’s team published research in Synlett in 27 | CAS: 72571-06-3

Synlett published new progress about 72571-06-3. 72571-06-3 belongs to oxazolidine, auxiliary class Oxazole,Bromide,Benzene, name is 5-(4-Bromophenyl)oxazole, and the molecular formula is C4H11NO, Name: 5-(4-Bromophenyl)oxazole.

Vinay Kumar, Koravangala S. published the artcileA One-Pot Tandem Approach for the Synthesis of 5-(Het)aryloxazoles from Substituted (Het)aryl Methyl Alcohols and Benzyl Bromides, Name: 5-(4-Bromophenyl)oxazole, the publication is Synlett (2016), 27(9), 1363-1366, database is CAplus.

A new modified van Leusen strategy was developed for the synthesis of biol. significant 5-substituted oxazoles I (R = Ph, 2-furyl, etc.) by the reaction of either [(het)aryl]methyl alcs. RCH2OH or benzyl bromides RCH2Br as precursors with tosylmethyl isocyanide (TosMIC) under basic conditions. This method is efficient, takes place under mild reaction conditions, and is tolerant of various functional groups with high yield.

Synlett published new progress about 72571-06-3. 72571-06-3 belongs to oxazolidine, auxiliary class Oxazole,Bromide,Benzene, name is 5-(4-Bromophenyl)oxazole, and the molecular formula is C4H11NO, Name: 5-(4-Bromophenyl)oxazole.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem