Top Picks: new discover of Oxazolidin-2-one

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Chemistry involves the study of all things chemical – chemical processes, chemical compositions and chemical manipulation – in order to better understand the way in which materials are structured, how they change and how they react in certain situations. Synthetic Route of 497-25-6

This manuscript describes a highly enantioselective conjugate hydrazine addition to alpha,beta-unsaturated imides. The achiral template used has a significant impact on product enantioselectivity. Reactions at lower temperatures provide a protocol to add substituted hydrazines with selectivity resulting in the formation of a single pyrazolidinone product (>98:2 selectivity). A variety of chiral pyrazolidinones with potential as chiral auxiliaries and ligands are accessible through the new conjugate addition methodology. Copyright

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H998NO – PubChem