Chemistry can be defined as the study of matter and the changes it undergoes. Synthetic Route of 16251-45-9. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.Synthetic Route of 16251-45-9, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, molecular formula is C10H11NO2, introducing its new discovery.
Dienophiles of the general structure (EtO)2P(O)CH{double bond, long}CHCOX have been prepared, where X represents an oxazolidinone chiral auxiliary. Use of the (S)-4-isopropyl-5,5-diphenyl-1,3-oxazolidin-2-one auxiliary gave Diels-Alder adducts with several cyclic and acyclic dienes. The crystal structures of the main cyclohexa-1,3-diene and 2,3-dimethylbutadiene adducts formed during reactions in the presence of dialkylaluminium halides are consistent with a reaction, which is stereoselectively endo with respect to the carbonyl group and occurs on the less hindered face of the dienophile when aluminium is chelated between the two carbonyl groups.
The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis.I hope my blog about 16251-45-9 is helpful to your research. Synthetic Route of 16251-45-9
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2150NO – PubChem