So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Maki, Toshikatsu; Ishihara, Kazuaki; Yamamoto, Hisashi researched the compound: Pyridin-3-ylboronic acid hydrochloride( cas:265664-63-9 ).Synthetic Route of C5H7BClNO2.They published the article 《New boron(III)-catalyzed amide and ester condensation reactions》 about this compound( cas:265664-63-9 ) in Tetrahedron. Keywords: boron catalysis carboxylic acid esterification amidation green chem; polystyrene bound alkylated boronopyridinium salt preparation catalysis esterification amidation; Ritter addition catalysis benzodioxaborole; crystal structure cyclocondensed dodecamer quaternized boronopyridinium iodide; mol structure cyclocondensed dodecamer quaternized boronopyridinium iodide. We’ll tell you more about this compound (cas:265664-63-9).
In 1996, the authors reported that benzeneboronic acids bearing electron-withdrawing groups at the meta- or para-position are highly effective catalysts for the amide condensation reaction in less-polar solvents. The authors now report that N-alkyl-4-boronopyridinium halides are more effective catalysts than the previous ones in more polar solvents. N-Alkyl-4-boronopyridinium halides are effective not only for amide condensation between equimolar mixtures of carboxylic acids and amines but also for the esterification of α-hydroxycarboxylic acids in alc. solvents. Furthermore, perchlorocatecholborane is more effective than areneboronic acids for the amide condensation of sterically demanding carboxylic acids. Lewis acid-assisted Bronsted acid (LBA), which was prepared from a 1:2 M mixture of boric acid and tetrachlorocatechol, is effective for the Ritter reaction from alcs. and nitriles to amides. The crystal and mol. structures of a cyclocondensed dodecamer of 4-borono-1-methylpyridinium iodide were determined by x-ray crystallog.
There is still a lot of research devoted to this compound(SMILES:OB(C1=CC=CN=C1)O.[H]Cl)Synthetic Route of C5H7BClNO2, and with the development of science, more effects of this compound(265664-63-9) can be discovered.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem