The important role of Isoxazolidine hydrochloride

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39657-45-9, Name is Isoxazolidine hydrochloride, belongs to oxazolidine compound, is a common compound. category: oxazolidineIn an article, once mentioned the new application about 39657-45-9.

A three-step synthesis of N-(9-(9-phenylfluorenyl)-L-alaninal (5) from alanine is described.Exposure to silica or nonnucleophilic base causes no detectable racemization of this alpha-amino aldehyde.The 9-(9-phenylfluorenyl) N-protecting group also maintains the configurational integrity of alpha-amino aldehyde 5 during C-C bond-forming reactions, providing enantiomerically pure products from Wittig reaction, aldol condensation, and addition of Grignard reagent.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1289NO – PubChem