497-25-6, Name is Oxazolidin-2-one, belongs to oxazolidine compound, is a common compound. HPLC of Formula: C3H5NO2In an article, once mentioned the new application about 497-25-6.
A highly efficient, two-step, one-pot synthetic strategy for amides and peptides was developed by employing ynamides as novel coupling reagents under extremely mild reaction conditions. The ynamides not only are effective for simple amide and dipeptide synthesis but can also be used for peptide segment condensation. Importantly, no racemization was detected during the activation of chiral carboxylic acids. Excellent amidation selectivity toward amino groups in the presence of -OH, -SH, -CONH2, ArNH2, and the NH of indole was observed, making the protection of these functional groups unnecessary in amide and peptide synthesis.
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Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H621NO – PubChem