SDS of cas: 1194-22-5. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 6-Hydroxy-2-methylpyrimidin-4(3H)-one, is researched, Molecular C5H6N2O2, CAS is 1194-22-5, about Synthesis of triple [14C]-labeled moxonidine. Author is Czeskis, Boris A..
The synthesis of radiolabeled antihypertensive compound [14C3]moxonidine I was accomplished based on condensation of [1-14C]acetamidine with di-Et [1,3-14C2]malonate to form [2,4,6-14C3]-4,6-dihydroxy-2-methylpyrimidine. Subsequent nitration, chlorination, and hydrogenation of the latter gave [2,4,6-14C3]-4,6-dichloro-2-methyl-5-aminopyrimidine. The final product was obtained after the coupling of the above aminopyrimidine with 1-acetylimidazolidin-2-one, followed by hydrolysis using sodium methoxide.
This compound(6-Hydroxy-2-methylpyrimidin-4(3H)-one)SDS of cas: 1194-22-5 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem