Direct β-Alkylation of Aldehydes via Photoredox Organocatalysis was written by Terrett, Jack A.;Clift, Michael D.;MacMillan, David W. C.. And the article was included in Journal of the American Chemical Society in 2014.Product Details of 2043-21-2 This article mentions the following:
In the presence of a bis(C,N-dimethylphenylpyridinyl)(di-tert-butylbipyridinyl)iridium(III) complex as a photocatalyst and dicyclohexylamine as an organocatalyst, aldehydes such as octanal underwent chemoselective photochem. β-alkylation with electron-deficient alkenes such as H2C:CRR1 (R = H, Ph, 1-naphthyl, 4-MeOC6H4, 4-FC6H4, 4-ClC6H4, 2-BrC6H4; R1 = PhCH2O2C, MeO2C, NC, PhSO2, 2-oxo-3-oxazolidinylcarbonyl) under blue LED light to give β-substituted aldehydes such as OHCCH2CH(CH2Bu)CH2CHRR1 (R = H, Ph, 1-naphthyl, 4-MeOC6H4, 4-FC6H4, 4-ClC6H4, 2-BrC6H4; R1 = PhCH2O2C, MeO2C, NC, PhSO2, 2-oxo-3-oxazolidinylcarbonyl) in 50-83% yields. The reaction used the photochem. oxidation of enamines generated from aldehydes to yield enaminyl radicals as the key step. A benzyl oxodecenoate and a benzyl oxononenoate underwent chemoselective and stereoselective cyclization under the alkylation conditions to yield oxoethylcycloalkylacetates in 54% and 47% yields. Fluorescence quenching and EPR studies were used to study the reaction mechanism. In the experiment, the researchers used many compounds, for example, 3-Acryloyloxazolidin-2-one (cas: 2043-21-2Product Details of 2043-21-2).
3-Acryloyloxazolidin-2-one (cas: 2043-21-2) belongs to oxazolidine derivatives. A common way to produce multisubstituted oxazolidines is by means of cycloaddition reactions. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.Product Details of 2043-21-2
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem