Enantioselective Cu-catalyzed 1,4-addition of Me3Al to a 4,4-disubstituted cyclohexa-2,5-dienone was written by Takemoto, Yoshiji; Kuraoka, Satoru; Hamaue, Naoko; Aoe, Keiichi; Hiramatsu, Hajime; Iwata, Chuzo. And the article was included in Tetrahedron on November 4,1996.Computed Properties of C13H17NO2 The following contents are mentioned in the article:
A series of chiral enantiomerically pure 2-aryloxazolines was synthesized. (4S)-2-(2′,6′-dimethoxyphenyl)-4-isopropyloxazoline proved to be an efficient chiral ligand for the Cu-catalyzed conjugate addition of Me3Al to cyclohexadienone, and by using 20 mol% of this ligand, 1,4-adduct was obtained in 68% ee. In addition, TBDMSOTf is crucial for the asym. conjugate addition to proceed with good chem. yield and high ee. This study involved multiple reactions and reactants, such as (S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8Computed Properties of C13H17NO2).
(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8) belongs to oxazolidine derivatives.Oxazolidines are readily available also from propargyl amines. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.Computed Properties of C13H17NO2
135948-04-8;(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol;The future of 135948-04-8;New trend of C13H17NO2;function of 135948-04-8