Tag: M.W:100-200

152305-23-2, (S)-4-(4-Aminobenzyl)oxazolidin-2-one is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

(S)-4-(4-Aminobenzyl)-l,3-oxazolidin-2-one (IX) (100 g) was charged in water (400 ml, 4.0 volumes) and cone. HCl (200 ml, 2.0 volumes) was added at 25-30¡ãC. The solution was cooled to 5 to -10¡ãC and a solution of sodium nitrite (54 g, 1.5 equivalents) in water (400 ml, 4.0 volumes) was added whilst maintaining the temperature below -5¡ãC. After completion of the addition, the reaction mixture was stirred for 3 hours resulting in the formation of the diazonium chloride (XV) in solution.

152305-23-2, As the paragraph descriping shows that 152305-23-2 is playing an increasingly important role.

Reference£º
Patent; GENERICS [UK] LIMITED; MYLAN DEVELOPMENT CENTRE PRIVATE LIMITED; WO2009/44211; (2009); A1;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2346-26-1,Oxazolidine-2,4-dione,as a common compound, the synthetic route is as follows.

EXAMPLE 1 A mixture of (E)-4-[2-[5-methyl-2-(3-methylphenyl)-4-oxazolyl]ethoxy]cinnamaldehyde (1.20 g), 2,4-oxazolidinedione (0.525 g), piperidine (0.09 g) and ethanol (20 ml) was heated for 5 hours under reflux. The reaction mixture was poured into water, which was acidified with 2N HCl, followed by extraction with ethyl acetate. The ethyl acetate layer was washed with water, dried (MgSO4) and, then, concentrated. The concentrate was purified by means of a silica gel column chromatography. From the fractions eluted with chloroform-methanol (50:1) was obtained 5-[4-[2-[5-methyl-2-(3-methylphenyl)-4-oxazolyl]ethoxy]cinnamylidene]-2,4-oxazolidinedione (0.51 g, 34%). Recrystallization from dichloromethane-methanol gave pale yellow prisms, m.p.213-214 C.

2346-26-1, 2346-26-1 Oxazolidine-2,4-dione 97389, aoxazolidine compound, is more and more widely used in various.

Reference£º
Patent; Takeda Chemical Industries, Ltd.; US5665748; (1997); A;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem