Tag: 438.4731

Doerner, Barbara et al. published their research in Peptide Science in 2005 | CAS: 252554-78-2

Fmoc-Ala-Ser[Psi(Me,Me)Pro]-OH (cas: 252554-78-2) belongs to oxazolidine derivatives. A common way to produce multisubstituted oxazolidines is by means of cycloaddition reactions. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.Related Products of 252554-78-2

Pseudoproline dipeptides in Fmoc-solid phase peptide synthesis was written by Doerner, Barbara;Steinauer, Rene;Barthelemy, Sophie;White, Peter D.. And the article was included in Peptide Science in 2005.Related Products of 252554-78-2 This article mentions the following:

This paper presents an overview on the application of Mutter’s pseudoproline dipeptides in the synthesis of difficult, phosphorylated and long peptides. Their use in enantiomerization-free fragment condensation is also described. In the experiment, the researchers used many compounds, for example, Fmoc-Ala-Ser[Psi(Me,Me)Pro]-OH (cas: 252554-78-2Related Products of 252554-78-2).

Fmoc-Ala-Ser[Psi(Me,Me)Pro]-OH (cas: 252554-78-2) belongs to oxazolidine derivatives. A common way to produce multisubstituted oxazolidines is by means of cycloaddition reactions. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.Related Products of 252554-78-2

Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

 

Zhang, Qiang et al. published their research in Proceedings of the National Academy of Sciences of the United States of America in 2014 | CAS: 252554-78-2

Fmoc-Ala-Ser[Psi(Me,Me)Pro]-OH (cas: 252554-78-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol. Oxazolidines are weaker bases (pKa 6–7) than parent β-amino alcohols and found to be more lipophilic than the parent compound at physiological pH.Category: oxazolidine

Synthesis of granulocyte-macrophage colony-stimulating factor as homogeneous glycoforms and early comparisons with yeast cell-derived material was written by Zhang, Qiang;Johnston, Eric V.;Shieh, Jae-Hung;Moore, Malcolm A. S.;Danishefsky, Samuel J.. And the article was included in Proceedings of the National Academy of Sciences of the United States of America in 2014.Category: oxazolidine This article mentions the following:

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a medicinally important glycoprotein, used as an immunostimulant following bone-marrow transplant. On the basis of reports of its potential utility as an anticancer vaccine adjuvant, we undertook to develop a synthetic route toward single-glycoform GM-CSF. We describe herein a convergent total synthesis of GM-CSF aglycon and two homogeneous glycoforms. Anal. and biol. studies confirm the structure and activity of these synthetic congeners. In the experiment, the researchers used many compounds, for example, Fmoc-Ala-Ser[Psi(Me,Me)Pro]-OH (cas: 252554-78-2Category: oxazolidine).

Fmoc-Ala-Ser[Psi(Me,Me)Pro]-OH (cas: 252554-78-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol. Oxazolidines are weaker bases (pKa 6–7) than parent β-amino alcohols and found to be more lipophilic than the parent compound at physiological pH.Category: oxazolidine

Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem