169048-83-3, (S)-5-(Chloromethyl)oxazolidin-2-one is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(S)-6(21.7 mg, 160 mumol) in N,N-dimethylformamide (DMF)(4.0 mL) was added to a solution of 4 (43.5 mg, 123 mumol).K2CO3 (204 mg, 1.48 mmol) was added, and the reactionmixture was stirred at 140C for 45 min. The mixture wasfiltered, and the filtrate was diluted with H2O (5 mL) and thenextracted with CHCl3 (3¡Á30 mL). The combined extract waswashed with brine (20 mL), dried, and concentrated in vacuoto give a residue (60 mg). Chromatography on a silica gel columnwith n-hexane-EtOAc (1 : 2-1 : 1) as the eluent gave (S)-1(26.8 mg, 48%) as a colorless powder. 1H-NMR (400 MHz,CDCl3) delta: 7.35 (2H, s), 5.79 (1H, br), 5.02 (1H, ddt, J=8.7, 6.2,5.0 Hz), 4.82 (1H, br), 4.20 (2H, d, J=5.0 Hz), 3.91 (1H, dd,J=8.7, 6.2 Hz), 3.82 (1H, t, J=8.7 Hz), 3.67 (3H, s), 3.39 (2H, q,J=6.7 Hz), 2.74 (2H, t, J=6.7 Hz). HR-FAB-MS m/z 450.9498[M+H]+ (Calcd for C14H17Br2N2O5: 450.9504). [alpha]D25 +21.4(c=0.1, MeOH).
169048-83-3, As the paragraph descriping shows that 169048-83-3 is playing an increasingly important role.
Reference£º
Article; Sirimangkalakitti, Nachanun; Yokoya, Masashi; Chamni, Supakarn; Chanvorachote, Pithi; Plubrukrn, Anuchit; Saito, Naoki; Suwanborirux, Khanit; Chemical and Pharmaceutical Bulletin; vol. 64; 3; (2016); p. 258 – 262;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem