Tag: 141.1247

Switching Diastereoselectivity in Catalytic Enantioselective (3+2) Cycloadditions of Azomethine Ylides Promoted by Metal Salts and Privileged Segphos-Derived Ligands was written by Caleffi, Guilherme S.;Larranaga, Olatz;Ferrandiz-Saperas, Marcos;Costa, Paulo R. R.;Najera, Carmen;de Cozar, Abel;Cossio, Fernando P.;Sansano, Jose M.. And the article was included in Journal of Organic Chemistry in 2019.Name: 3-Acryloyloxazolidin-2-one This article mentions the following:

Catalytic enantioselective 1,3-dipolar cycloaddition between imino esters and electrophilic alkenes, employing chiral metal complexes derived from copper(I) and silver(I) salts and (S)-DM- or (S)-DTBM-Segphos as ligands produces diastereodivergently exo- or endo-cycloadducts, resp. The effect of the functional group of the dipolarophile and the fine tuning of the catalyst plays an important role in promoting reverse diastereoselectivities. The origins of exptl. observed enantioselectivity and diastereoselectivity data, as well as the origin of the observed switched endo/exo ratios, are also explained by means of d. functional theory calculations In the experiment, the researchers used many compounds, for example, 3-Acryloyloxazolidin-2-one (cas: 2043-21-2Name: 3-Acryloyloxazolidin-2-one).

3-Acryloyloxazolidin-2-one (cas: 2043-21-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are commonly used as metal ligands in asymmetric catalysis, synthetic intermediates in organic synthesis, and also used as the protecting groups.Name: 3-Acryloyloxazolidin-2-one

Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

A Unified Stereodivergent Strategy for Prostaglandin and Isoprostanoid Synthesis was written by Valli, Matteo;Chiesa, Francesco;Gandini, Andrea;Porta, Alessio;Vidari, Giovanni;Zanoni, Giuseppe. And the article was included in Journal of Organic Chemistry in 2014.Computed Properties of C6H7NO3 This article mentions the following:

Acetoxyfulvene I surrendered to asym. Diels-Alder cycloaddition, paving the way to the development of a unified strategy for the stereodivergent synthesis of both prostaglandins and isoprostanoids. In fact, the cycloadduct II was subsequently converted to a common intermediate, which through two different stereoselective pathways afforded the two lactones III and IV, which are key building blocks in the synthesis of prostaglandins and isoprostanoids, resp. In the experiment, the researchers used many compounds, for example, 3-Acryloyloxazolidin-2-one (cas: 2043-21-2Computed Properties of C6H7NO3).

3-Acryloyloxazolidin-2-one (cas: 2043-21-2) belongs to oxazolidine derivatives. Oxazolidines are commonly obtained by reaction of strained heterocycles, mainly aziridines. Oxazolidines are commonly used as metal ligands in asymmetric catalysis, synthetic intermediates in organic synthesis, and also used as the protecting groups.Computed Properties of C6H7NO3

Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Asymmetric nitrone cycloadditions and their application to the synthesis of enantiopure pyrrolidine and pyrrolizidine derivatives was written by Argyropoulos, Nikolaos G.;Panagiotidis, Theodoros;Coutouli-Argyropoulou, Evdoxia;Raptopoulou, Catherine. And the article was included in Tetrahedron in 2007.HPLC of Formula: 2043-21-2 This article mentions the following:

The cycloaddition reactions of a pair of chiral pyrroline-N-oxides derived from D-ribose, e.g. I, with some typical mono- and disubstituted alkenes are reported. In all these reactions with monosubstituted alkenes as well as with di-Me maleate the preferred stereochem. outcome of the cycloaddition step comes from a 5-exo-anti transition state whereas stereoisomers from the 5-exo-syn transition state are also present as minor adducts. In the reaction with di-Me fumarate the major adduct comes from a 4-exo-5-endo-syn transition state. The further behavior of the obtained isoxazolidines, e.g. II [R = EtO, MeO₂C, (2-oxooxazolidin-3-yl)carbonyl], upon reductive ring opening conditions depends on the kind and the geometry of the preexisting substituents and they are transformed to enantiomerically pure pyrrolidine or pyrrolizidinone derivatives In the experiment, the researchers used many compounds, for example, 3-Acryloyloxazolidin-2-one (cas: 2043-21-2HPLC of Formula: 2043-21-2).

3-Acryloyloxazolidin-2-one (cas: 2043-21-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.HPLC of Formula: 2043-21-2

Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Rare earth metal triflates promoted Diels-Alder reactions in ionic liquids was written by Sarma, Diganta;Kumar, Anil. And the article was included in Applied Catalysis, A: General in 2008.HPLC of Formula: 2043-21-2 This article mentions the following:

Rare earth metal triflates, when used with ionic liquids can promote Diels-Alder reactions of dienes and dienophiles, where the catalytic activity of the triflates is enhanced by ionic liquids It is possible to recover and reuse the ionic liquid phase with triflates to give comparable yields and stereoselectivity even after six cycles. In the experiment, the researchers used many compounds, for example, 3-Acryloyloxazolidin-2-one (cas: 2043-21-2HPLC of Formula: 2043-21-2).

3-Acryloyloxazolidin-2-one (cas: 2043-21-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.HPLC of Formula: 2043-21-2

Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem