In an article, author is Wang, Wengui, once mentioned the application of 90319-52-1, Name is (R)-4-Phenyloxazolidin-2-one, molecular formula is C9H9NO2, molecular weight is 163.1733, MDL number is MFCD00192393, category is oxazolidines. Now introduce a scientific discovery about this category, Application In Synthesis of (R)-4-Phenyloxazolidin-2-one.
Palladium-catalyzed allylation of trifluoromethylated ketene aminoacetals
A new development in the palladium-catalyzed allylation reaction of trifluoromethylated ketene aminoacetals was reported. These nucleophilic reagents were prepared by adding aminoalcohols to methyl 3,3,3-trifluoro-2-trifluoromethylpropanoate. The asymmetric version of the allylation reaction was investigated using chiral oxazolidine-based starting materials or chiral palladium catalysts. Asymmetric allylic alkylation was carried out with up to 74% ee using a chiral catalyst. However, no improvement was observed using double stereodifferentiation. These results provided a novel access for trifluoromethylated all-carbon quaternary carbon centers. (C) 2014 Elsevier B.V. All rights reserved.
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Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem