Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 90319-52-1, Name is (R)-4-Phenyloxazolidin-2-one, SMILES is O=C1OC[C@@H](C2=CC=CC=C2)N1, in an article , author is Ganesan, Vaidyanathan Vaidyanathan, once mentioned of 90319-52-1, COA of Formula: C9H9NO2.
Elastic compliance of fibrillar assemblies in type I collagen
Fibrillary assemblies of Type I collagen find important applications in tissue engineering and as matrices for biophysical studies. The mechanical and structural properties of these structures are governed by factors such as protein concentration, temperature, pH and ionic strength. This study reports on an impedance based analysis of the elastic compliance of fibrillary assemblies of Type I collagen using quartz crystal microbalance with dissipation (QCM-D) at a fundamental frequency of 5 MHz and overtones (n = 3,5,7,9,11). Here, In situ partial fibrillation of the adsorbing collagen followed by its fibrillary assemblies on hydrophilic gold coated quartz surface have been crosslinked using Gallic acid (GA), Chromium (III) gallate (Cr-GA), Catechin (Cat), Tetrakis (hydroxymethyl)phosphonium sulfate (THPS) and Oxazolidine (Ox). This approach allows direct comparison of how viscoelastic properties track the structural evolution of the fiber and network length scales. The collagen crosslinking shows significant positive impact on the protein’s mechanical behaviour and on the type of cross linking agents used. The elastic modulus increases as collagen < GA < THPS < Cr-GA < Cat < Ox. Atomic force microscopic studies on the adsorbed collagen after cross linking confirmed the presence of fibrous assemblies. The results indicate stabilization and reinforcement through strong physical entanglement between the molecules of collagen as well as chemical interaction between collagen matrix and fibrils during cross linking. The elastic compliance evaluated from Delta Dissipation/Delta freq. from QCM-D showed that cross linking with GA, Cr-GA and Ox resulted in flexible fibrillary network while agents like THPS and Cat showed elastic moduli similar to that of pure collagen. Results suggest that optimal collagen-crosslinking agent ratio and degree of crosslinking of collagen can help tailor the mechanical properties for specific applications in design of bio-materials of these composites. But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 90319-52-1, you can contact me at any time and look forward to more communication. COA of Formula: C9H9NO2.
Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem