One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Safety of 5-(Chloromethyl)oxazolidin-2-one, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 22625-57-6, Name is 5-(Chloromethyl)oxazolidin-2-one, molecular formula is C4H6ClNO2
Bioisosteric replacement and related analogs in the design, synthesis and evaluation of ligands for muscarinic acetylcholine receptors
Previous structure-activity relationship studies involving a series of lactone-based muscarinic ligands identified a lead compound containing a diphenylmethylpiperazine moiety (4; IC50 = 340 nM). The purpose of the present work is to investigate 1,3-benzodioxoles, 4,4-diethyl substituted tetrahydrofurans, 5-substituted oxazolidinones and chromones as bioisosteric replacements for the lactone ring in a novel series of muscarinic ligands. The approach provided compounds with improved % inhibition values and identified a non-selective muscarinic ligand with an IC50 value of 280 nM. The structure-activity relationship for this new series will be discussed. Selected compounds were evaluated in preliminary assays for subtype selectivity and were found to be non-selective.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Safety of 5-(Chloromethyl)oxazolidin-2-one, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 22625-57-6, in my other articles.
Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H1432NO – PubChem