Electric Literature of 497-25-6, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 497-25-6, Oxazolidin-2-one, introducing its new discovery.
Steric and electronic requirements of amide and ester groups in benzylidenemalonates
Stereoisomeric benzylidinemalonates have been synthesised. In the case of N-(2-ethoxycarbonyl-3-phenylpropenoyl)-2-oxazolidinone, both E- and Z-isomers could be obtained, but the Z-isomer isomerised (> 95%) to the E-isomer in the presence of catalytic amounts of Rh(I) complex catalysts. For ethyl tert-butylamidobenzalmalonate, the Z-isomer initially predominates under Knoevenagel conditions, but is very readily converted into the more stable E-isomer, which is here isolated stereoisomerically pure and is the only product of other synthetic routes. The configuration of benzylidinemalonates was established in two cases by X-ray crystallography, and the relative stability of the isomeric forms correctly simulated by MM2 calculations. In both the amide and oxazolidinone series, asymmetric hydrogenation catalysed by cationic Rh complexes gave a configurationally stable product cleanly but in low e.e..
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 497-25-6. In my other articles, you can also check out more blogs about 497-25-6
Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H377NO – PubChem