Solomon, Marissa R. published the artcileIsolation and syn elimination of a Peterson adduct to obtain optically pure product in the diastereoselective synthesis of oxazolidinone-functionalized enecarbamates, SDS of cas: 4042-43-7, the main research area is Peterson adduct oxazole phenylpropiophenone preparation elimination diphenylbutenyloxazolidinone.
The Peterson reaction of (4R)-N-(trimethylsilyl)methyl-4-alkyloxazolidin-2-one gives (E/Z)-(4R)-N-(2′,3′-diphenylbut-1′-enyl)-4-alkyloxazolidin-2-ones (enecarbamates) with increasing (Z)-selectivity and moderate-to-high diastereoselectivity in the individual E isomer as a function of increasing temperature X-ray structure of the Peterson adduct, (4R,3’S)-N-(2′,3′-diphenyl-2′-hydroxy-but-1′-enyl)-4-isopropyloxazolidin-2-one reveals the rationale for the formation of a single isomer through syn elimination. The optically pure enecarbamates obtained with the Peterson adduct were further employed for photochem. and photophys. studies.
Letters in Organic Chemistry published new progress about Elimination reaction. 4042-43-7 belongs to class oxazolidine, name is (R)-4-Methyloxazolidin-2-one, and the molecular formula is C4H7NO2, SDS of cas: 4042-43-7.
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem