95530-58-8, (R)-4-Isopropyloxazolidin-2-one is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,95530-58-8
The R-type Evans cofactor was added to a 250 ml dry reaction flask and dissolved in 70 ml of dry THF. The solution was cooled to -78 C and n-BuLi (18.5 ml, 46.3 mmol) was added slowly. After 30 min, (E) -2-methyl-2-butyryl chloride (5.0 g, 42.5 mmol) was added and the reaction was allowed to proceed for 30 min and the temperature was raised to 0 C. (20 ml of X3). The combined organic layers were washed with saturated brine (40 ml), dried over anhydrous sulfuric acid (20 ml) and concentrated in vacuo. The organic layer was extracted with ethyl acetate,Dried and filtered. The filtrate was concentrated under reduced pressure and the residue was subjected to column chromatography (elution conditions, petroleum ether: ethyl acetate = 10: 1) to give the product as a white solid (yield: 94%).
95530-58-8 (R)-4-Isopropyloxazolidin-2-one 641505, aoxazolidine compound, is more and more widely used in various.
Reference£º
Patent; Fudan University; Lei, Xinsheng; Lin, Guojiang; Xu, Qianqian; Zhao, Qun; (29 pag.)CN104341276; (2016); B;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem