Simple exploration of 90319-52-1

90319-52-1 (R)-4-Phenyloxazolidin-2-one 730425, aoxazolidine compound, is more and more widely used in various fields.

90319-52-1, (R)-4-Phenyloxazolidin-2-one is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

R-4-phenyl-2-oxazolidone (4 g, 24.5 mmol) was dissolved in 50 mL of dichloromethane, and then triethylamine (5.2 mL, 1.5 eq) was added therein. Subsequently, 2-fluoro-propionyl chloride (1.3 eq) was slowly added dropwise at 0¡ã C.5¡ãAfter the raw materials were completely reacted indicating by TLC, filtering the solid, drying the organic phase by concentration, then 20 mL of methanol was added. The resulting mixture was stirred for 3 h and filtered to give 5 g white solid in a yield of 86.0percent., 90319-52-1

90319-52-1 (R)-4-Phenyloxazolidin-2-one 730425, aoxazolidine compound, is more and more widely used in various fields.

Reference£º
Patent; TOPHARMAN SHANGHAI CO., LTD.; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES; TOPHARMAN SHANDONG CO., LTD.; Wang, Guan; Jiang, Xiangrui; Gong, Xudong; Chen, Weiming; Zhu, Fuqiang; Zhang, Rongxia; Zhao, Xianguo; US2015/284351; (2015); A1;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem