Research on new synthetic routes about 67914-60-7

From this literature《Pd-catalyzed aminations of aryltriazolones: effective synthesis of hydroxyitraconazole enantiomers》,we know some information about this compound(67914-60-7)HPLC of Formula: 67914-60-7, but this is not all information, there are many literatures related to this compound(67914-60-7).

HPLC of Formula: 67914-60-7. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone, is researched, Molecular C12H16N2O2, CAS is 67914-60-7, about Pd-catalyzed aminations of aryltriazolones: effective synthesis of hydroxyitraconazole enantiomers. Author is Tanoury, Gerald J.; Senanayake, Chris H.; Hett, Robert; Kuhn, Amy M.; Kessler, Donald W.; Wald, Stephen A..

A palladium-catalyzed amination of triazolone I by piperazine II was used as the key step in an efficient synthesis of highly enantiomerically pure hydroxyitraconazole (III). II (>99% ee) was prepared by reaction of an achiral phenol precursor with the corresponding dioxolyl tosylate (>99% ee).

From this literature《Pd-catalyzed aminations of aryltriazolones: effective synthesis of hydroxyitraconazole enantiomers》,we know some information about this compound(67914-60-7)HPLC of Formula: 67914-60-7, but this is not all information, there are many literatures related to this compound(67914-60-7).

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem