Synthetic Route of 144542-43-8, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 144542-43-8, (R)-Methyl 2-oxooxazolidine-4-carboxylate, introducing its new discovery.
Enantiomer recognition of amides by dirhodium(II) tetrakis[methyl 2-oxopyrrolidine-5(s)-carboxylate]
Association constants of the chiral dirhodium(II) carboxamidate Rh 2(5S-MEPY)4 with Lewis bases including acetonitrile and amides have been determined by UV-vis titration experiments. With chiral lactams and acyclic acetamides in their R- and S-configurations equilibrium constants with chiral dirhodium carboxamidates are measures of chiral differentiation, and equilibrium constant ratios as high as three have been determined. From equilibrium associations with acetamide, N-methylacetamide, and N,N-dimethylacetamide, as well as equilibrium constants for lactams and acyclic amides, higher values occur when both the amide carbonyl oxygen and N-H are bound to Rh2(5S-MEPY)4. This cooperative bonding mode is confirmed by NMR measurements that show a distinctive shift of a N-H absorption, as well as perturbation of the ligands on dirhodium compound, and they suggest N-H association with a ligated oxygen of Rh2(5S-MEPY)4. Measurements were made on the dirhodium(II) compound from which protective axial ligands have been removed to enhance their reliability.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 144542-43-8. In my other articles, you can also check out more blogs about 144542-43-8
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H1484NO – PubChem