One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, 497-25-6, such as the rate of change in the concentration of reactants or products with time.In a article, authors is Mittag, Tina, mentioned the application of 497-25-6, Name is Oxazolidin-2-one, molecular formula is C3H5NO2
Direct entry to peptidyl ketones via SmI2-mediated C-C bond formation with readily accessible N-peptidyl oxazolidinones
(Chemical Equation Presented) In this work, a new method for the preparation of peptidyl ketones is presented employing a SmI2/H 2O-mediated coupling of N-peptidyl oxazolidinones with electron-deficient alkenes. The requisite peptide imides were easily prepared by solution-phase peptide synthesis starting from an N-acyl oxazolidinone derivative of an amino acid. Importantly, they could be used directly in the C-C bond-forming step without the need for further functionalization. Coupling of these peptide derivatives with a second peptide possessing an N-terminal acryloyl group leads to ketomethylene isosteres of glycine-containing peptides. This method represents an alternative means for ligating two small peptides through a C-C bond-forming step.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. 497-25-6, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 497-25-6, in my other articles.
Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H821NO – PubChem