Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Electric Literature of 3190-70-3. Introducing a new discovery about 3190-70-3, Name is (S)-4-Isobutyloxazolidine-2,5-dione
The mechanisms of the reactions of 4-alkyloxazolidinediones (1) (N-carboxy alpha-amino acid anhydrides(NCAs)) with alpha-amino acid benzyl ester p-toluenesulfonates (2) were investigated in acetonitrile containing triethylamine at low and room temperatures.Two types of reactions were observed: (1) the polymerization of NCAs was initiated with a small amount of 2 to produce polypeptides (6), and (2) the dipeptide benzyl esters (4) were produced by the stepwise reaction of NCAs with the esters.Both the polymerization and the dipeptide formation (1+2) seemed to be initiated by the nucleophilic attack of the amino group of the ester on the C-5 carbon of NCAs.The polymerization proceeded when the side chains of the amino acid esters (R2) were more bulky than those of the NCAs (R1).On the contrary, dipeptide esters were produced when the side chains of the NCAs (R1) were more bulky than those of the esters (R2).
Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.Read on for other articles about 3190-70-3
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H1520NO – PubChem