Transition metal oxo, sulfido and amido complexes as catalysts of nucleophilic addition reactions was written by Grubbs, Robert H.; Toste, F. Dean. And the patent was published on December 27,2002.HPLC of Formula: 163165-92-2 The following contents are mentioned in the patent:
Methods are provided for carrying out nucleophilic addition reactions using oxo, sulfido or amido complexes of transition metals as reaction catalysts. Exemplary catalysts are oxo complexes of Group 7 transition metals, with Re(V) oxo complexes, including dioxo complexes, preferred. Nucleophilic addition reactions that can be catalyzed using the present methods include silylation, hydrosilylation, hydroamination, silylmetalation, carbometalation, aldol reactions, hydro- and carbometalation initiated cyclization/polymerization, and epoxide/aziridine opening. The invention also pertains to novel transition metal complexes that have utility in catalyzing such reactions. For example, [ReO2L2]CN was prepared from ReO(AsPh3)2Cl3 and (4S)-(+)-phenyl-α-phenyloxazolin-2-oxazoline-2-acetonitrile. This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2HPLC of Formula: 163165-92-2).
(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.HPLC of Formula: 163165-92-2
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem