Preparation method of chiral aromatic amine compounds by alkylation and rearrangement was written by Guo, Chang; Chang, Xihao; Zhang, Qinglin. And the patent was published on March 20,2018.HPLC of Formula: 1045894-43-6 The following contents are mentioned in the patent:
The invention relates to the preparation method of chiral aromatic amine compounds, i.e., I and II, by alkylation and rearrangement. The prepared chiral aromatic amine compounds have high optical purity (ee value above 99%), has wide application in field of bioactive materials, chiral ligands and chiral catalysts, and can be derived for the further preparation of racemized or chiral aromatic imide ligands as the catalyst for asym. catalytic reactions. This study involved multiple reactions and reactants, such as (R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol (cas: 1045894-43-6HPLC of Formula: 1045894-43-6).
(R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol (cas: 1045894-43-6) belongs to oxazolidine derivatives. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries. Chiral oxazolidines are widely used as chiral auxiliaries, chiral ligands, protecting and/or directing groups in a variety of asymmetric transformations, thanks also to their easy cleavage or their further elaboration possibilities.HPLC of Formula: 1045894-43-6
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem