2-[(4R)-4,5-dihydro-4-R-2-oxazolyl]phenyl diphenylphosphonate, and synthesis method and application thereof was written by Luo, Mei. And the patent was published on July 20,2011.SDS of cas: 1045894-43-6 The following contents are mentioned in the patent:
Title compound as shown formula I is synthesized by allowing to react 2-cyanophenol with d-amino alc. in O2-free anhydrous chlorobenzene in the presence of ZnCl2 under refluxing for 24 h to obtain 2-[(4R)-4,5-dihydro-4-R-2-oxazolyl]phenol, and then allowing to react with diphenylphosphonyl chloride in O2-free anhydrous toluene-triethylamine under refluxing for 24 h, wherein R = -CH2CH(CH3)2, -CH(CH3)2, Ph, or -CH2Ph. The compound can be used as chiral catalyst and shows good catalytic activity and high enantioselectivity during asym. synthesis of 2-methylbenzaldehyde. This study involved multiple reactions and reactants, such as (R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol (cas: 1045894-43-6SDS of cas: 1045894-43-6).
(R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol (cas: 1045894-43-6) belongs to oxazolidine derivatives. Oxazolidines that are the precursor to bisoxazolidines are in effect mono-oxazolidines. They are also used as moisture scavengers in polyurethane and other systems. Chiral oxazolidines are widely used as chiral auxiliaries, chiral ligands, protecting and/or directing groups in a variety of asymmetric transformations, thanks also to their easy cleavage or their further elaboration possibilities.SDS of cas: 1045894-43-6
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem