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(Chemical Equation Presented) Chiral 1-aryl-6-(hydroxymethyl)-2- ketopiperazines can be prepared via an operationally simple, 6-exo epoxide ring-opening cyclization to form the ketopiperazine C6-N1 bond in high yields and with excellent enantiomeric purity.
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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H2552NO – PubChem