Electric Literature of C3H3NO. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Oxazole, is researched, Molecular C3H3NO, CAS is 288-42-6, about Antiproliferative activity of thiazole and oxazole derivatives: A systematic review of in vitro and in vivo studies. Author is Guerrero-Pepinosa, Nancy Y.; Cardona-Trujillo, Maria C.; Garzon-Castano, Sandra C.; Veloza, Luz Angela; Sepulveda-Arias, Juan C..
A review. Thiazole and oxazole are compounds with a heterocyclic nucleus that have attracted the attention of medicinal chem. due to the great variety of biol. activities that they enable. In recent years, their study has increased, finding a wide range of biol. activities, including antifungal, antiparasitic, anti-inflammatory, and anticancer activities. This systematic review provides evidence from the literature on the antiproliferative and antitumor activities of thiazole and oxazole and their derivatives from 2014 to Apr. 2020. Three bibliog. databases were consulted (PubMed, Web of Science, and Scopus), and a total of 32 studies were included in this paper based on our eligibility criteria. The anal. of the activity-structure relationship allows us to conclude that most of the promising compounds identified contained thiazole nuclei or derivatives
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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem