Related Products of 16251-45-9, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 16251-45-9, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, SMILES is O=C1O[C@H](C2=CC=CC=C2)[C@H](C)N1, belongs to oxazolidines compound. In a article, author is Lu, Zheng, introduce new discover of the category.
Convenient approach to chiral 4-monosubstituted 1,3-oxazolidine-2-thiones
Chiral 4-monosubstituted 1,3-oxazolidine-2-thiones are regarded as one of the modified version of Evans auxiliaries in asymmetric aldol condensation, which can generate two adjacent chiral carbon centers in one time They have advantages over Evans auxiliaries in some aspects, however, their application is highly limited by their preparation approaches as toxic or flammable chemicals are involved. Here, a mild and applicable procedure for preparing the chiral oxazolidine-2-thione auxiliaries has been developed in this article. Potassium ethylxanthate and the corresponding chiral amino alcohols as the starting material in absolute ethanol are mixed and the mixture are heated under reflux for 1h in open air to provide 1,3-oxazolidine-2-thiones chiral auxiliaries in moderate to excellent yields. [GRAPHICS] .
Related Products of 16251-45-9, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 16251-45-9 is helpful to your research.
Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem