The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 6-Hydroxy-2-methylpyrimidin-4(3H)-one( cas:1194-22-5 ) is researched.Application of 1194-22-5.Jadhav, Pandurang M.; Sarangapani, Radhakrishnan; Patil, Rajendra S.; Pandey, Raj K. published the article 《Process Optimization, Product Profile Mapping, and Intensification of 1,1-Diamino-2,2-dinitroethylene》 about this compound( cas:1194-22-5 ) in Organic Process Research & Development. Keywords: process optimization product profile mapping intensification diaminodinitroethylene safety. Let’s learn more about this compound (cas:1194-22-5).
Industrialization of a chem. process needs an understanding of process chem., optimal process envelope, and the best choice of operation. 1,1-Diamino-2,2-dinitroethylene (FOX-7) is a new generation, and the highly insensitive compound finds application in high-energy formulations as well as preparation of novel high-energy compounds The present study highlights efforts made for establishing a continuous process for FOX-7. The intermediates of nitration of 2-methylpyrimidine-4,6-dione were isolated and characterized by spectroscopic tools. Reaction kinetics was also derived for the formation of intermediates. Product profiles of the reaction were evaluated on deriving expressions for various reactors. The simultaneous effect of heat and reaction was evaluated in a tubular reactor to obtain the runaway reaction condition. The effective reactor scheme was evaluated, designed, and experimented. Process intensification was carried out in a continuous set up comprising various contact patterns. The present study delivered a safe and productive method for FOX-7 processing.
《Process Optimization, Product Profile Mapping, and Intensification of 1,1-Diamino-2,2-dinitroethylene》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(6-Hydroxy-2-methylpyrimidin-4(3H)-one)Application of 1194-22-5.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem