One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Quality Control of (S)-4-Phenyl-3-propionyloxazolidin-2-one, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 184363-66-4, Name is (S)-4-Phenyl-3-propionyloxazolidin-2-one, molecular formula is C12H13NO3
Evans Enolates: Structures and Mechanisms Underlying the Aldol Addition of Oxazolidinone-Derived Boron Enolates
The soft enolization of an acylated oxazolidinone using di-n-butylboron triflate (n-Bu2BOTf) and trialkylamines and subsequent aldol addition was probed structurally and mechanistically using a combination of IR and NMR spectroscopies. None of the species along the reaction coordinate show a penchant for aggregating. Complexation of the acylated oxazolidinone by n-Bu2BOTf was too rapid to monitor, as was the subsequent enolization with Et3N (triethylamine). The preformed n-Bu2BOTf·Et3N complex, displaying muted Lewis acidity and affiliated tractable rates, reveals a rate-limiting complexation via a transition structure with a complicated counterion. n-Bu2BOTf·i-Bu3N bearing a hindered amine shifts the rate-limiting step to proton transfer. Rate studies show that the aldol addition with isobutyraldehyde occurs as proffered by others.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Quality Control of (S)-4-Phenyl-3-propionyloxazolidin-2-one, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 184363-66-4, in my other articles.
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2272NO – PubChem