Reference of 1676-86-4, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 1676-86-4, (S)-Benzyl (4-(2,5-dioxooxazolidin-4-yl)butyl)carbamate, introducing its new discovery.
A novel amphiphilic multi-block copolymer conjugated with both a near infrared fluorescence probe and drug has been designed and prepared by means of ring-opening polymerization (ROP) of N-Carboxy Anhydride (NCA) monomers following a Reversible Addition-Fragmentation Chain Transfer (RAFT) polymerization. At first, an amino group-containing RAFT agent was synthesized and it served as an initiator for the sequential ROP of aspartic acid beta-benzyl ester N-carboxy anhydride (Asp-NCA) and epsilon-carbobenzoxy-l- lysine NCA (ZLLys-NCA). Then the multi-block copolymer was prepared by a succeeding RAFT polymerization of poly(ethylene glycol) methyl ether acrylate (OGEA). At the end, both anticancer drug doxorubicin and hydrophobic aminocyanine dye were chemical conjugated to the block copolymer via a hydrazone or amide bond, respectively. The obtained NIRF copolymer and its micelles were characterized by nuclear magnetic resonance (NMR), gel permeation chromatography (GPC), dynamic light scattering (DLS), and UV-vis and fluorescence spectrophotometry. The prodrug has strong fluorescence in the near infrared region and shows pH-responsive drug release behavior, and it has potential application in the theranostics of cancer.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 1676-86-4. In my other articles, you can also check out more blogs about 1676-86-4
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2746NO – PubChem