Application In Synthesis of Oxazolidin-2-one, Career opportunities within science and technology are seeing unprecedented growth across the world, and those who study chemistry or another natural science at university now have increasingly better career prospects. In a article, 497-25-6, molcular formula is C3H5NO2, introducing its new discovery.
A highly site-selective amidation reaction of substituted 2,4-dichloroazines is reported. Palladium acetate/1,1?-bis(diphenylphosphino)ferrocene (dppf) was identified as the optimal catalyst system, producing >99:1 C-2/C-4 selectivity for most examples. The generality of this transformation was demonstrated through a survey of a diverse amide/substituted 2,4-dichloroazine scope, leading to the preparation of the desired C-2 amidated products in good to excellent yields.
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Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H1185NO – PubChem