The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: Oxazole, is researched, Molecular C3H3NO, CAS is 288-42-6, about Biological Significance of Imidazole-based Analogues in New Drug Development, the main research direction is review biol significance imidazole new drug development anticancer heterocyclic; Imidazole; analgesic and anti-inflammatory; anti-tubercular; anticancer; antiviral; heterocyclic.Safety of Oxazole.
A review. In the field of heterocyclic medicinal chem., especially five-membered ring structures containing a nitrogen atom, imidazole core is an imperative aromatic heterocycle which is usually present in naturally occurring products and synthetic bioactive mols. The occurrence of imidazole moiety in therapeutic compounds may be beneficial in terms of improving water-soluble properties due to its two nitrogen atoms which leads to the creation of hydrogen bonds. The imidazole nucleus has also been recognized as an important isostere of triazole, pyrazole, thiazole, tetrazole, oxazole, amide etc. for the purpose of designing and development of various biol. active mols. Moreover, imidazole core as an attractive binding site could interact with diverse cations and anions as well as biomols. through different reactions in the human biol. system thus displaying extensive biol. activities. This effort thoroughly provides a wide-ranging assessment in current drug discovery and developments of imidazolebased analogs in the entire series of synthetic medicinal chem. as antibacterial and antifungal, anticancer, anti-tubercular, analgesic and anti-inflammatory, anti-neuropathic, antihypertensive, anti-allergic, anti-parasitic, antiviral, antidepressant, anti-obesity and so on, altogether with their prospective approaches in diagnostic and pathol. field. It is expected that the present review will be supportive on behalf of new opinions in the search for rational strategies of more efficacious and less toxic medicinal agents and drugs containing imidazole core.
Different reactions of this compound(Oxazole)Safety of Oxazole require different conditions, so the reaction conditions are very important.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem