Palladium catalyzed oxidation of ynamides using dimethyl sulfoxide as oxidant: a facile way to synthesize α-ketoamide derivatives was written by Meng, Tuanjie;Feng, Cuilan;Liu, Lantao;Wang, Tao;Xu, Kai;Zhao, Wenxian. And the article was included in Youji Huaxue in 2016.Application of 888329-88-2 This article mentions the following:
A series of α-ketoamide derivatives were obtained from the palladium catalyzed oxidation of ynamides using cheap and readily available DMSO as oxidant and solvent under room temperature The structures of all products were characterized by 1H NMR, 13C NMR, IR and HRMS. This protocol has some distinct advantages of mild conditions, simple work-up, readily available starting materials and fast reaction rate. In the experiment, the researchers used many compounds, for example, 3-(Phenylethynyl)oxazolidin-2-one (cas: 888329-88-2Application of 888329-88-2).
3-(Phenylethynyl)oxazolidin-2-one (cas: 888329-88-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.Application of 888329-88-2
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem