Landfill leachate as a mirror of today’s disposable society: Pharmaceuticals and other contaminants of emerging concern in final leachate from landfills in the conterminous United States was written by Masoner, Jason R.;Kolpin, Dana W.;Furlong, Edward T.;Cozzarelli, Isabelle M.;Gray, James L.. And the article was included in Environmental Toxicology and Chemistry in 2016.Application of 1665-48-1 This article mentions the following:
Final leachates (leachate after storage or treatment processes) from 22 landfills in 12 states were analyzed for 190 pharmaceuticals and other contaminants of emerging concern (CECs), which were detected in every sample, with the number of CECs 1-58 (median =22). In total, 101 different CECs were detected in leachate samples, including 43 prescription drugs, 22 industrial chems., 15 household chems., 12 nonprescription drugs, 5 steroid hormones, and 4 animal/plant sterols. The most frequently detected CECs were lidocaine (91%, local anesthetic), cotinine (86%, nicotine degradate), carisoprodol (82%, muscle relaxant), bisphenol A (77%, component of plastics and thermal paper), carbamazepine (77%, anticonvulsant), and N,N-diethyltoluamide (68%, insect repellent). Concentrations of CECs spanned 7 orders of magnitude, ranging from 2.0 ng/L (estrone) to 17,200,000 ng/L (bisphenol A). Concentrations of household and industrial chems. were the greatest (∼1000-1,000,000 ng/L), followed by plant/animal sterols (∼1000-100,000 ng/L), nonprescription pharmaceuticals (∼100-10,000 ng/L), prescription pharmaceuticals (∼10-10,000 ng/L), and steroid hormones (∼10-100 ng/L). The CEC concentrations in leachate from active landfills were significantly greater than those in leachate from closed, unlined landfills (p =0.05). The CEC concentrations were significantly greater (p <0.01) in untreated leachate compared with treated leachate. The CEC concentrations were significantly greater in leachate disposed to wastewater treatment plants from modern lined landfills than in leachate released to groundwater from closed, unlined landfills (p =0.04). The CEC concentrations were significantly greater (p =0.06) in the fresh leachate (leachate before storage or treatment) reported in a previous study compared with the final leachate sampled for the present study. Environ Toxicol Chem 2015;9999:1-13, Published 2015 SETAC. This article is a US Government work and is in the public domain in the USA. In the experiment, the researchers used many compounds, for example, 5-((3,5-Dimethylphenoxy)methyl)oxazolidin-2-one (cas: 1665-48-1Application of 1665-48-1).
5-((3,5-Dimethylphenoxy)methyl)oxazolidin-2-one (cas: 1665-48-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.Application of 1665-48-1
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem