Category: oxazolidine. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone, is researched, Molecular C12H16N2O2, CAS is 67914-60-7, about 18F-Deoxyfluorination of Phenols via Ru π-Complexes. Author is Beyzavi, Hudson; Mandal, Debashis; Strebl, Martin G.; Neumann, Constanze N.; D’Amato, Erica M.; Chen, Junting; Hooker, Jacob M.; Ritter, Tobias.
The deficiency of robust and practical methods for 18F-radiofluorination is a bottleneck for positron emission tomog. (PET) tracer development. Here, we report the first transition-metal-assisted 18F-deoxyfluorination of phenols. The transformation benefits from readily available phenols as starting materials, tolerance of moisture and ambient atm., large substrate scope, and translatability to generate doses appropriate for PET imaging.
This compound(1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone)Category: oxazolidine was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem