One-pot synthesis of alkynylthiocyanates by phase-transfer reagent was written by Li, Ming;Song, Wangze;Dong, Kun;Zheng, Yubin. And the article was included in Tetrahedron Letters in 2020.Quality Control of 3-(Phenylethynyl)oxazolidin-2-one This article mentions the following:
The thiocyano-group widely exists in natural products and drug structures. A novel one-pot synthesis of alkynylthiocyanates from terminal alkynes, [hydroxy(tosyloxy)iodo]benzene and potassium thiocyanate by phase-transfer reagent 18-crown-6, involving the hypervalent iodine intermediates in transition metal-free conditions, was developed. The internal alkynylthiocyanates could be used to synthesize some important compounds such as 5-thiocyanato-1,2,3-triazoles and (Z)-α-thiocyanato-vinyl trifluoromethanesulfonate. In the experiment, the researchers used many compounds, for example, 3-(Phenylethynyl)oxazolidin-2-one (cas: 888329-88-2Quality Control of 3-(Phenylethynyl)oxazolidin-2-one).
3-(Phenylethynyl)oxazolidin-2-one (cas: 888329-88-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds are well-known chiral auxiliaries and strategic molecular moieties in chemistry since they can effectively mask or mimic amino acid units or amino alcohols. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.Quality Control of 3-(Phenylethynyl)oxazolidin-2-one
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem