The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone, is researched, Molecular C12H16N2O2, CAS is 67914-60-7, about Stereoselective syntheses of both enantiomers of ketoconazole from (R)- and (S)-epichlorohydrin, the main research direction is ketoconazole enantiomer stereoselective synthesis.Product Details of 67914-60-7.
Stereoselective syntheses of both enantiomers of ketoconazole (I) from com. available (R)- or (S)-epichlorohydrin has been developed. The key step of these syntheses involves the selective substitution of the methylene chlorine atom by benzoate on a mixture of (2S,4R)-II and (2R,4R)-II or of their enantiomers, followed by crystallization of the corresponding cis-benzoates, from which (+)- or (-)-I were obtained as described for (±)-I. The ee’s of (+)- and (-)-ketoconazole were determined by HPLC on the CSP Chiralcel OD-H.
Although many compounds look similar to this compound(67914-60-7)Product Details of 67914-60-7, numerous studies have shown that this compound(SMILES:CC(N1CCN(C2=CC=C(O)C=C2)CC1)=O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem