C2-Symmetric 2,2′-Bipyridine-α,α’-1-adamantyl-diol Ligand: Bulky Iron Complexes in Asymmetric Catalysis was written by Lauzon, Samuel;Schouwey, Lionel;Ollevier, Thierry. And the article was included in Organic Letters in 2022.HPLC of Formula: 2043-21-2 This article mentions the following:
The synthesis of a chiral 2,2′;-bipyridine-α,α’-1-adamantyl-diol ligand was achieved starting from com. available materials. The bulky ligand was synthesized in three steps in 40% overall yield and stereoselectivities up to 98% de and >99.5% ee for the S,S enantiomer. The absolute configuration and structural insights of an heptacoordinated 2,2′-bipyridine-α,α’-1-Ad-diol/FeII chiral complex were obtained from single crystal diffraction anal. The newly synthesized ligand was used in iron-catalyzed asym. Mukaiyama aldol, thia-Michael and Diels-Alder reactions. In the experiment, the researchers used many compounds, for example, 3-Acryloyloxazolidin-2-one (cas: 2043-21-2HPLC of Formula: 2043-21-2).
3-Acryloyloxazolidin-2-one (cas: 2043-21-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds are well-known chiral auxiliaries and strategic molecular moieties in chemistry since they can effectively mask or mimic amino acid units or amino alcohols. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries.HPLC of Formula: 2043-21-2
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem