On October 1, 2010, Lang, Kai; Park, Jongwoo; Hong, Sukwon published an article.COA of Formula: C8H15NO2 The title of the article was Development of Bifunctional Aza-Bis(oxazoline) Copper Catalysts for Enantioselective Henry Reaction. And the article contained the following:
Base-functionalized aza-bis(oxazoline) ligands were prepared to explore the concept of dual activation through the Lewis acid and a tethered tertiary amine base. The catalytic activity of the Cu complex was evaluated for the asym. Henry reaction. Compared with a corresponding unfunctionalized copper complex with external 1-benzyl-4-ethylpiperazine base, the ethylpiperazine-functionalized aza-bis(oxazoline) copper catalyst I resulted in rate acceleration (2.5 times) as well as improved enantioselectivity (72% ee vs 92% ee). The experimental process involved the reaction of (S)-4-Isopropyl-5,5-dimethyloxazolidin-2-one(cas: 168297-86-7).COA of Formula: C8H15NO2
The Article related to chiral bifunctional bisoxazoline ligand preparation stereoselective henry reaction catalyst, aryl aldehyde copper chiral base functionalized ligand henry reaction, benzylic alc nitro derivative stereoselective preparation, henry reaction kinetic copper ligand base reaction order and other aspects.COA of Formula: C8H15NO2
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem