Drug screening method development for paper spray coupled to a triple quadrupole mass spectrometer was written by Jett, Rachel;Skaggs, Christine;Manicke, Nicholas E.. And the article was included in Analytical Methods in 2017.Safety of 5-((3,5-Dimethylphenoxy)methyl)oxazolidin-2-one This article mentions the following:
Paper spray mass spectrometry is a direct anal. method in which compounds are extracted and ionized from biofluids dried on paper. It is an attractive option for performing rapid drug screening because it is fast (the entire sample anal. takes <2 min), simple (there is no sample preparation or chromatog.), and sensitive (low ng mL-1 levels of many drugs can be detected from dried blood spots). Here, we discuss method development for paper spray mass spectrometry on a triple quadrupole mass spectrometer. Specifically, detection criteria, selected reaction monitoring (SRM) ratio tolerance, fragment ion selection, selectivity, and signal to blank considerations are all addressed. 134 drugs and drug metabolites commonly encountered in forensic toxicol. analyses were spiked into blood at concentrations reasonable for post-mortem drug screening applications. Detection of some 130 drug and drug metabolites using a single paper spray MS/MS is shown for these spike and recover experiments In the experiment, the researchers used many compounds, for example, 5-((3,5-Dimethylphenoxy)methyl)oxazolidin-2-one (cas: 1665-48-1Safety of 5-((3,5-Dimethylphenoxy)methyl)oxazolidin-2-one).
5-((3,5-Dimethylphenoxy)methyl)oxazolidin-2-one (cas: 1665-48-1) belongs to oxazolidine derivatives. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries.Safety of 5-((3,5-Dimethylphenoxy)methyl)oxazolidin-2-one
Referemce:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem